How it works

Venebio Opioid Advisor uses multiple demographic and clinical variables that are automatically identified and retrieved from the patient’s electronic medical records or other sources. The algorithm then uses proprietary logic to create a quantified, personalized risk profile for each patient based on reference data gleaned from tens of millions of patients who have previously been treated with opioids. Venebio Opioid Advisor then calculates each patient’s risk score and predicted probability of experiencing OIRD during the next six months.

Flexible Application

Venebio Opioid Advisor can function as a clinical decision support (CDS) tool and integrate directly with electronic medical records, or with other systems such as an analytics warehouse, population health platform, or health information exchange (HIE) to deliver point-of- care information to clinicians. Alternatively, Venebio Opioid Advisor can evaluate an entire patient database and provide a report identifying all at-risk patients.

Further, the tool can be reliably and accurately operated by trained non-physician healthcare professionals (e.g., PA, RN, LPN), saving valuable time for other clinicians.



Patients identified as high-risk could benefit from risk mitigation measures, such as:

  • Patient and caregiver education
  • Prescription of take-home naloxone for administration by family members or caregivers as a potential rescue medication
  • Increased caution in opioid selection and dose escalation
  • Specific interventions customized to each individual patient's risk factor profile